{"id":224,"date":"2021-07-20T16:07:14","date_gmt":"2021-07-20T16:07:14","guid":{"rendered":"https:\/\/franckplouraboue.net\/?page_id=224"},"modified":"2025-02-17T14:22:45","modified_gmt":"2025-02-17T14:22:45","slug":"networks-analysis-and-bio-imaging","status":"publish","type":"page","link":"https:\/\/franckplouraboue.net\/?page_id=224","title":{"rendered":"Network analysis & bio-imaging"},"content":{"rendered":"\t\t
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\n\t\t\t\t\t\t\t\t\t\"\"<\/a>Networks play an important role in many engineering and applied problems such as water or gas transport in pipe networks, electric distributions, river basins, etc. They also represent a key concept in several biological contexts such as vascular networks<\/strong>, metabolic reaction networks<\/strong>, epidemiology, etc. In our group, we are mainly interested in networks for pipe flow distribution systems<\/strong>, micro-vascular networks perfusion distribution<\/strong>, and metabolic reaction modeling.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\"\"Regarding pipe flow distribution<\/strong> and blood flow modeling<\/strong>, many issues are of interest, including pressure and flow distribution modeling, pressure pulsed wave propagation<\/strong> and heat or mass transport<\/strong> inside these networks, relationships between applied conditions and flow distributions, etc.<\/p>\n

The first step consists in characterizing the structural properties of these graphs<\/strong>. For vascular networks, it necessitates performing 3D image distributions as well as image post-processing and 3D reconstruction of skeletonized vessels<\/strong>.
\nThese very complex structural networks being known, their simplification or the resulting identification of structural and functional units<\/strong> are of great interest in many contexts.
\nModeling of flow and transport in these networks have many application domains.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\"\"For many years, we have developed specific tissue preparation and imaging techniques for 3D high-resolution imaging of micro-vascular networks using X-ray tomography or laser sheet microscopy (Plourabou\u00e9 et al. 2004<\/a>, Kennel et al. 2020<\/a>). We have also developed specific imaging analysis post-processing to fill gaps in interrupted vessel imaging (Risser et al. J. Biomedical imaging).\n\nWe then found structural units associated with:\n